Pulse Ox and Congenital Heart Defect Research

Pulse oximetry screening to detect critical congenital heart disease has been studied relatively intensively, but not in a large U.S. population.

Present this research to legislators and policy makers when advocating for standard pulse oximetry screening. If you’re new to pulse oximetry screening, consider reading this overview from Children’s National Hospital.

At this point, the most compelling pieces of evidence are a paper published in Pediatrics and a large study from the UK, both should be part of any advocacy work.


Pulse oximetry screening for congenital heart defects in newborn infants (PulseOx): a test accuracy study

Accuracy of Pulse Oximetry Measurement of Heart Rate of Newborn Infants in the Delivery Room

First Day of Life Pulse Oximetry Screening to Detect Congenital Heart Defects

Impact of pulse oximetry screening on the detection of duct dependent congenital heart disease: a Swedish prospective screening study in 39 821 newborns

Pulse oximetry screening as a complementary strategy to detect critical congenital heart defects

Accuracy of pulse oximetry in screening for congenital heart disease in asymptomatic newborns: a systematic review.

 Other Academic Articles

American Academy of Pediatrics: Strategies for Implementing Screening for Critical Congenital Heart Disease, Kemper et al.

American Academy of Pediatrics: Endorsement of Health and Human Services Recommendation for Pulse Oximetry Screening for Critical Congenital Heart Disease

Screening Algorithm from the Kemper Paper 

It Is Time for Routine Neonatal Screening By Pulse Oximetry, Hoffman 2010

Congenital Heart Disease Screening: Policy, Politics and Practice

Pulse Oxmietry Screening for Unrecognized Congenital Heart Disease in Neonates

Physical Examination and Pulse Oximetry in Newborn Infants: Out with the Old, in with the New?

Role of Pulse Oximetry in Examining Newborns for Congenital Heart Disease. A Scientific Statement From the American Heart Association and American Academy of Pediatrics

 Learn More

Non-academic resources are also available.

Children’s National Pulse Oximetry Screening Program

CHD Babies: Pulse Oximetry



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